innovexbio universal fc receptor blocker

innovex

For Circulation cytometry assays: Fc receptors are present on leukocytes (white blood cells), many cell traces along with totally different cell varieties in every human and animal cells/tissues. Fc receptors gives rise to non-specific Fc receptor-staining in motion cytometry assays by binding of Fc space of antibodies and isotype controls to Fc receptors of the cells. Non-specific Fc receptors staining is perhaps eradicated by incubating cells with INNOVEX Fc Receptor Blocker for a variety of Circulation cytometry assays equal to CD phenotyping, leukemia typing and cell line analysis. (See instruction a part of this info sheet).

For IHC, ICC, IF testing: The binding of the Fc space of main and/or secondary antibody and immunoglobulin
isotypes to the Fc receptors present on cells/tissues give rise to non-specific Fc receptor staining. Specimens rich in Fc receptors embrace spleen, lymphoid tissues, lymphomas, tonsil, lymph nodes, bone marrow, blood smears and liver. Others embrace tissues and cell preps meant for staining for CD markers; Immunoglobulins (Igs), Kappa and Lambda and tumor cell traces that express Fc receptors.

innovexbio universal fc receptor blocker
innovexbio universal fc receptor blocker

PRODUCT DESCRIPTION

Innovex Fc Receptor Blocker is a UNIVERSAL Fc Blocker related to blocking all types of Fc receptors equal to Fc-gamma receptors of kind I,II and III; Fc -epsilon receptors kind I and II; Fc –alpha receptors, Fcα/ µR and FcRn. Innovex Fc Blocker does NOT comprise antibodies, Immunoglobulins or immunoglobulin fragments. INNOVEX Fc Blocker is perhaps universally utilized to dam all types of Fc receptors in all-species along with human, mouse and all-animals This Frequent Fc Block might be utilized in a variety of Immunoassays equal to IHC, ICC, Immunofluorescence and Circulation cytometry. INNOVEX UNIVERSAL Fc BLOCK is acceptable for blocking Fc receptors in frozen and paraffin tissuesections and cyto preps of human and all-animal species. INNOVEX Fc Blocker can be usually used for eliminating background staining in thoughts cells/tissues.

 

INTRODUCTION

Fc receptors (FcRs) are glycoproteins of approximate molecular weights of 50-70 kD. They’re extensively expressed
all by the immune cells. Fc receptors are present on leukocytes equal to monocytes, tissue macrophages, B cells,
granulocytes (eosinophils, basophils, neutrophils), NK cells and some T cells. Fc receptors are moreover present on mast cells, follicular dendritic cells, epithelial cells, endothelial cells, hepatocytes and langerhans cells amongst others. There are a variety of types of Fc receptors (FcR) which can be categorised based totally on the antibody that they acknowledge. There are individuals who have good affinity for the Fc space of monomeric IgG antibody and are known as Fc-Gamma receptors, individuals who bind to IgA antibody are known as Fc-alpha receptors and individuals who bind IgE antibody are known as Fc-epsilon receptors.

Non explicit Fc receptors staining in assays equal to IHC, ICC, Immunofluorescence (IF) and motion cytometry could find yourself from the binding of the Fc space of the primary and/or secondary antibody or immunoglobulin isotypes to the Fc receptors of the cells. Eliminating Fc receptor staining is fascinating in IHC, ICC, IF and Circulation cytometry assays for the purpose of right info evaluation.

 

 

VAHTS Target Capture Universal Blockers and Post-PCR Primer Mix for MGI-SI

NCM101-02 96 rxns
EUR 1751.2

VAHTS Target Capture Universal Blockers and Post-PCR Primer Mix for Illumina-TS

NC101-01 24 rxns
EUR 528

VAHTS Target Capture Universal Blockers and Post-PCR Primer Mix for Illumina-TS

NC101-02 96 rxns
EUR 1751.2

10 x Universal Blocking Buffer

GR103005 200 mL
EUR 129

Fc Receptor Blocker, 60 ml; Ready-To-Use

NB309 60 ml
EUR 745
Description: Fc Receptor Blocker, 60 ml; Ready-To-Use

Fc Receptor Blocker, 15 ml; Ready-To-Use

NB309-15 15 ml
EUR 295
Description: Fc Receptor Blocker, 15 ml; Ready-To-Use

Fc Receptor Blocker, 30 ml; Ready-To-Use

NB309-30 30 ml
EUR 425
Description: Fc Receptor Blocker, 30 ml; Ready-To-Use

Fc Receptor Blocker; 4X Concentrate, 15 ml Conce

NB309-4X-15 15 ml of 4X
EUR 765
Description: Fc Receptor Blocker; 4X Concentrate, 15 ml Concentrate

Fc Receptor Blocker; 4X Concentrate, 40 ml Conce

NB309-4X-40 40 ml of 4X concentrate
EUR 1550
Description: Fc Receptor Blocker; 4X Concentrate, 40 ml Concentrate

Universal platform

INC1112 EACH
EUR 1434

Azide-Free Fc Receptor Blocker, 60 ml (Large volum

NB335-60 60 ml
EUR 755
Description: Azide-Free Fc Receptor Blocker, 60 ml (Large volume) Ready-To-Use

Universal Attachment

MIX1320 EACH
EUR 286.8

Universal V1-Puck

M-CP-111-021 1 PUCK
EUR 350
Description: Universal V1-Puck

Universal Oven UN30

OVE8314 EACH
EUR 1672.8

Universal Oven UN55

OVE8316 EACH
EUR 1952.4

Universal Oven UN75

OVE8318 EACH
EUR 2028

Universal Oven UF30

OVE8332 EACH
EUR 1911.6

Universal Oven UF55

OVE8334 EACH
EUR 2306.4

Universal Oven UF75

OVE8336 EACH
EUR 2433.6

UNIVERSAL BEER AGAR

U21-100-10kg 10 kg
EUR 1828.8

UNIVERSAL BEER AGAR

U21-100-2kg 2kg
EUR 444

UNIVERSAL BEER AGAR

U21-100-500g 500 g
EUR 164.4

Grant Universal Tray

BAT4622 EACH
EUR 314.4

Universal AC adapter

PIP3214 EACH
EUR 78

Universal Oven UN110

OVE8320 EACH
EUR 2598

Universal Oven UN160

OVE8322 EACH
EUR 3133.2

Universal Oven UN260

OVE8324 EACH
EUR 4148.4

Universal Oven UN450

OVE8326 EACH
EUR 5490

Universal Oven UN750

OVE8328 EACH
EUR 7356

Universal Oven UF110

OVE8338 EACH
EUR 2876.4

Universal Oven UF160

OVE8340 EACH
EUR 3740.4

Universal Oven UF260

OVE8342 EACH
EUR 4768.8

Leave a Reply

Your email address will not be published. Required fields are marked *

Blog PCR

Human monkeypox – After 40 years, an unintended consequence of smallpox eradication

Smallpox eradication, coordinated by the WHO and certified 40 years ago, led to the cessation of routine smallpox vaccination in most countries. It is estimated that over 70% of the world’s population is no longer protected against smallpox, and through cross-immunity, to closely related orthopox viruses such as monkeypox. Monkeypox is now a re-emerging disease. […]

Read More
Blog parg antibody

A Tale of Two Viruses: Coinfections of Monkeypox and Varicella Zoster Virus in the Democratic Republic of Congo

Recent enhanced monkeypox (MPX) surveillance in the Democratic Republic of Congo, where MPX is endemic, has uncovered multiple cases of MPX and varicella zoster virus (VZV) coinfections. The purpose of this study was to verify if coinfections occur and to characterize the clinical nature of these cases. Clinical, epidemiological, and laboratory results were used to […]

Read More